7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6212 | Combretastatin A4 | CA4,CRC 87-09 | Microtubule Associated |
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). | |||
T31857 | Fosbretabulin [free base] | Fosbretabulin,Combretastatin A-4,CA4DP | |
Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels. | |||
T60823 | IsoCA-4 | ||
isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1]. | |||
T35251 | YK-5-252 | YK 5 252,YK5-252,YK-5252 | |
YK-5-252 is a dual action combretastatin A-4 (CA-4) prodrug which releases CA-4 through a disulfide bond cleavage mechanism and contains a near-infrared (NIR) fluorophore. | |||
T32127 | HYS-32 | HYS 32 | |
HYS-32, as an analog of combretastatin A-4, can exert by enhancing connexin43 expression. | |||
T16386 | Ombrabulin hydrochloride | AVE8062 (hydrochloride),AC7700 (hydrochloride) | Microtubule Associated |
Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and has antivascular effects. Ombrabulin is a tubulin polymeriz... | |||
T68400 | STA-9584 | ||
STA-9584 is a potent vascular disrupting agent, which exhibits potent antitumor activity by selectively targeting microvasculature at both the center and periphery of tumors. In vitro, 2-methoxy-5-(5-(3,4,5-trimethoxyphe... |